Ischemia is defined as?

Ischemia is defined as?

• A. Increased blood flow to the tissue
• B. Tissue necrosis
• C. Reduced blood flow to the tissue
• D. Normal perfusion

Answer: (C)

Ischemia means reduced blood flow to tissue, so oxygen and nutrient delivery drops below what the tissue needs for normal function. That shortage forces the cells to rely more on anaerobic metabolism, leading to less ATP production and metabolic stress. If perfusion is restored quickly, function can recover; if it’s prolonged, the lack of oxygen can cause cellular injury and potentially tissue necrosis. This is different from simply having tissue necrosis, which is cell death itself, and it’s the opposite of increased blood flow or normal perfusion.

Ischemia means reduced blood flow to tissue, so oxygen and nutrient delivery drops below what the tissue needs for normal function. That shortage forces the cells to rely more on anaerobic metabolism, leading to less ATP production and metabolic stress. If perfusion is restored quickly, function can recover; if it’s prolonged, the lack of oxygen can cause cellular injury and potentially tissue necrosis. This is different from simply having tissue necrosis, which is cell death itself, and it’s the opposite of increased blood flow or normal perfusion.